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B4 Pharm Exam 1
B4 Pharm Exam 1 How hyperlipidemia leads to heart failure - hyperlip --> athero --> CHD (ie. angina, MI) and/or HTN --> heart failure Classes of Antihyperlipidemic Drugs - - HMG-CoA reductase inhibs (statins) - Bile acid sequestrants - Chol absorp inhibs - Fibrates - Niacin - Others incl PCSK9 inhibs, HDL elevs, HoFH Lipoprotein - transp form of lipids made up of lipids+prots since lipids insol in plasma Chylomicrons - lipoprot synth in intest made of dietary (exog) TGs+chol;...
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B4 Pharm Exam 1 How hyperlipidemia leads to heart failure - hyperlip --> athero --> CHD (ie. angina, MI) and/or HTN --> heart failure Classes of Antihyperlipidemic Drugs - - HMG-CoA reductase inhibs (statins) - Bile acid sequestrants - Chol absorp inhibs - Fibrates - Niacin - Others incl PCSK9 inhibs, HDL elevs, HoFH Lipoprotein - transp form of lipids made up of lipids+prots since lipids insol in plasma Chylomicrons - lipoprot synth in intest made of dietary (exog) TGs+chol;...